Cancer Research

Selected Mathematical Oncology papers

  • F. R. Adler. A modelling framework for cancer ecology and evolution. Journal of the Royal Society Interface, 21:20240099, 2024.
  • A. Bukkuri and F. R. Adler. Of criminals and cancer: The importance of social bonds and innate morality on cellular societies. Cells & Development, page 203964, 2024.
  • K. Jitmana, J. I. Griffiths, S. Fereday, A. DeFazio, D. Bowtell, A. O. C. Study, and F. R. Adler. Mathematical modeling of the evolution of resistance and aggressiveness of high-grade serous ovarian cancer from patient ca-125 time series. PLOS Computational Biology, 20:e1012073, 2024.
  • A. Bukkuri and F. R. Adler. Biomarkers or biotargets? using competition to lure cancer cells into evolutionary traps. Evolution, Medicine, and Public Health, page eoad017, 2023.
  • R. Emond, J. I. Griffiths, V. K. Grolmusz, A. Nath, J. Chen, E. F. Medina, R. S. Sousa, F. R. Synold, T. Adler, and A. H. Bild. Cell facilitation promotes growth and survival under drug pressure in breast cancer. Nat. Comm., 14:3851, 2023.
  • J. I. Griffiths, P. A. Cosgrove, E. M. Castaneda, A. Nath, J. Chen, F. R. Adler, J. T. Chang, Q. J. Khan, and A. H. Bild. Cancer cell communication with macrophages prevents T cell activation during emergence of cell cycle therapy resistance. Cancer Research, 83:4318--4318, 2023.
  • J. I. Griffiths, P. A. Cosgrove, E. M. Castaneda, A. Nath, J. Chen, F. R. Adler, J. T. Chang, Q. J. Khan, and A. H. Bild. Cancer cells subvert fibroblast function to promote a growth factor enriched tumor microenvironment in endocrine therapy resistant ER+ breast cancer. Cancer Research, 83:5693--5693, 2023.
  • J. West, F. Adler, J. Gallaher, M. Strobl, R. Brady-Nicholls, J. Brown, M. Roberson-Tessi, E. Kim, R. Noble, Y. Viossat, et al. A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation. Elife, 12:e84263, 2023.
  • F. R. Adler, A. R. Anderson, A. Bhushan, P. Bogdan, J. J. Bravo-Cordero, A. Brock, Y. Chen, E. Cukierman, K. E. DelGiorno, G. V. Denis, et al. Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Systems, 14:252--257, 2023.
  • F. R. Adler, S. R. Amend, C. J. Whelan, and E. Baratchart. From ecology to cancer biology and back again. Frontiers in Ecology and Evolution, 9, 2022.
  • C. K. Buhler, R. S. Terry, K. G. Link, and F. R. Adler. Do mechanisms matter? comparing cancer treatment strategies across mathematical models and outcome objectives. Mathematical Biosciences and Engineering, 18:6305--6327, 2021.
  • A. Bukkuri and F. R. Adler. Viewing cancer through the lens of corruption: Using behavioral ecology to understand cancer. Frontiers in Ecology and Evolution, 9:442, 2021.
  • J. I. Griffiths, J. Chen, P. A. Cosgrove, A. O’Dea, P. Sharma, C. Ma, M. Trivedi, K. Kalinsky, K. B. Wisinski, R. O’Regan, and I. Makhoul. Serial single-cell genomics reveals convergent subclonal evolution of resistance as patients with early-stage breast cancer progress on endocrine plus CDK4/6 therapy. Nature Cancer, 2021.
  • R. Beckman, I. Kareva, J. Pepper, and F. R. Adler. How should cancer models be constructed? Cancer Control, 27:1073274820962008, 2020.
  • J. I. Griffiths, P. Wallet, L. T. Pflieger, D. Stenehjem, X. Liu, P. A. Cosgrove, N. A. Leggett, J. A. McQuerry, G. Shrestha, M. Rosetti, G. Sunga, P. J. Moos, F. R. Adler, J. T. Chang, S. Sharma, and A. Bild. Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy. Proc. Nat. Acad. Sci., 117:16072--16082, 2020.
  • T. T. Le and F. R. Adler. Is mammography screening beneficial: an individual-based stochastic model for breast cancer incidence and mortality. PLoS Comp. Biol., 16:e1008036, 2020.
  • F. R. Adler and D. M. Gordon. Cancer ecology and evolution: Positive interactions and system vulnerability. Current Opinion in Systems Biology, 17:1--7, 2019.